I’m currently beginning the final year of my PhD in Medical Microbiology (comparative genomics of Pseudomonas aeruginosa) and have to decided to write about my experiences so far that might be useful to other students with the same problems and also comment on interesting research in microbial genomics, medical microbiology, bioinformatics and molecular evolution 🙂
“Like begets like is the fundamental law of biology and probably the oldest piece of genetic knowledge. During the 20th century – the last of this millennium – our understanding of inheritance has undergone several revolutionary changes; first with the rediscovery of Mendel’s laws in 1901, through the DNA double helix of Watson and Crick, and culminating, in the last decade, in DNA sequencing of genomes. Genetics changed from a subject concerned simply with the segregation of characters in crosses to the direct analysis of genes. This has led us to the insight that organisms are unique, complex systems in the natural world, which contain internal description of their structure, function, development and history encoded in the DNA sequences of their genes.” –Sydney Brenner.